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COL17A1 Polyclonal Antibody

     
  • WB - COL17A1 Polyclonal Antibody AP74015
    detail
  •  - COL17A1 Polyclonal Antibody AP74015
    detail
  •  - COL17A1 Polyclonal Antibody AP74015
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9UMD9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 150419 Da
Additional Information
Gene ID 1308
Other Names COL17A1 BP180 BPAG2
Dilution WB~~WB 1:500-2000, ELISA 1:10000-20000
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name COL17A1
Synonyms BP180, BPAG2
Function May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.
Cellular Location Cell junction, hemidesmosome. Membrane; Single- pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome [97 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane Note=Localized in the lamina lucida beneath the hemidesmosomes
Tissue Location Detected in skin (PubMed:8618013). In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) (PubMed:25676728). Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves
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Background

May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.

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$ 350.00
Cat# AP74015
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