POLDIP2 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IP |
---|---|
Primary Accession | Q9Y2S7 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 42033 Da |
Gene ID | 26073 |
---|---|
Other Names | POLDIP2 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | POLDIP2 {ECO:0000303|PubMed:26984527, ECO:0000312|HGNC:HGNC:23781} |
---|---|
Function | Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites (PubMed:24191025). May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1) (PubMed:24191025, PubMed:26984527). |
Cellular Location | Mitochondrion matrix. Nucleus Note=Mainly localizes to the mitochondrial matrix; a small fraction localizes in the nucleus. |

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