LSP1 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, ICC |
---|---|
Primary Accession | P33241 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa actin-binding protein; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 37192 Da |
Dilution | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human LSP1 |
Description | LSP1 is a 52 kDa leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils. The protein binds F-actin through its C-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion. LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | LSP1 |
---|---|
Synonyms | WP34 |
Function | May play a role in mediating neutrophil activation and chemotaxis. |
Cellular Location | Cell membrane; Peripheral membrane protein; Cytoplasmic side |
Tissue Location | Activated T-lymphocytes. |

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