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SNAP29 Antibody

Rabbit mAb

     
  •  - SNAP29 Antibody AP92796
    Western blot analysis of SNAP29 expression in (1) HeLa cell lysate; (2) Mouse brain lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession O95721
Reactivity Rat
Clonality Monoclonal
Other Names CEDNIK; SNAP29;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 28970 Da
Additional Information
Dilution WB 1:500~1:2000 IP 1:50
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human SNAP29
Description Involved in multiple membrane trafficking steps.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name SNAP29 (HGNC:11133)
Function SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions.
Cellular Location Cytoplasm. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9Z2P6}; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Cell projection, cilium membrane; Peripheral membrane protein. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic Localizes to the ciliary pocket from where the cilium protrudes
Tissue Location Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas
Research Areas
Citations (0)
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$ 385.00
$ 195.00
Cat# AP92796
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