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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-SIRPg / CD172g Reference Antibody (KWAR23)
Anti-SIRPg / CD172g Reference Antibody (KWAR23)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, Kinetics, Animal Model |
|---|---|
| Primary Accession | Q9P1W8 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | IgG4SP |
| Calculated MW | 143.4 KDa |
| Target/Specificity | SIRPg / CD172g |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | SIRPG |
|---|---|
| Synonyms | SIRPB2 |
| Function | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen- specific T-cell proliferation and costimulates T-cell activation. |
| Cellular Location | Membrane; Single- pass type I membrane protein |
| Tissue Location | Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection. |
Research Areas
Citations (0)
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$ 385.00
Cat# APR10072
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