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> home > Products > Primary Antibodies > Antibody Collections > Recombinant Antibodies > Anti-TNFSF13B / BAFF / CD257 Reference Antibody (tabalumab)
Anti-TNFSF13B / BAFF / CD257 Reference Antibody (tabalumab)
Recombinant Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, E, FTA |
|---|---|
| Primary Accession | Q9Y275 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | IgG4SP |
| Calculated MW | 145 KDa |
| Target/Specificity | TNFSF13B / BAFF / CD257 |
|---|---|
| Endotoxin | < 0.001EU/ µg,determined by LAL method. |
| Conjugation | Unconjugated |
| Expression system | CHO Cell |
| Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
| Name | TNFSF13B |
|---|---|
| Synonyms | BAFF, BLYS, TALL1, TNFSF20, ZTNF4 |
| Function | Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B- cells and the B-cell response. |
| Cellular Location | Cell membrane; Single-pass type II membrane protein |
| Tissue Location | Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# APR10464
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