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ICOSLG Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | O75144 |
| Other Accession | O75144 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone Names | ICOSLG |
| Calculated MW | Predicted: 33 kDa Observed: 60 kDa |
| Gene ID | 23308 |
|---|---|
| Alias Symbol | ICOSLG |
| Other Names | ICOSLG Antibody: GL50, Inducible T Cell Costimulator Ligand, B7-Related Protein, B7 Homolog, Inducible T-Cell Costimulator Ligand, B7-Like Protein Gl50, B7 Homologue, B7RP-1, ICOSL, B7-H2, B7RP1, B7H2, Transmembrane Protein B7-H2 ICOS Ligand, Inducible T-Cell Co-Stimulator Ligand, CD275 Antigen, ICOS Ligand, KIAA0653, ICOS-L, CD275, LICOS |
| Reconstitution & Storage | ICOSLG antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | ICOSLG Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ICOSLG |
|---|---|
| Synonyms | B7H2, B7RP1, ICOSL, KIAA0653 |
| Function | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells. |
Research Areas
Citations (0)
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Submit your citation using an Abcepta antibody to
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 379.00
Cat# ASC12120
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