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GYG2 Antibody (monoclonal) (M04)
Mouse monoclonal antibody raised against a partial recombinant GYG2.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O15488 |
| Other Accession | NM_003918 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3D10 |
| Calculated MW | 55184 Da |
| Gene ID | 8908 |
|---|---|
| Other Names | Glycogenin-2, GN-2, GN2, GYG2 |
| Target/Specificity | GYG2 (NP_003909, 392 a.a. ~ 501 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | GYG2 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
References
1.LC-MS/MS characterization of combined glycogenin-1 and glycogenin-2 enzymatic activities reveals their self-glucosylation preferences.Nilsson J, Halim A, Larsson E, Moslemi AR, Oldfors A, Larson G, Nilsson JBiochim Biophys Acta. 2013 Nov 14;1844(2):398-405. doi: 10.1016/j.bbapap.2013.11.002.
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