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GYG2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O15488 |
| Other Accession | NP_001073324.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55184 Da |
| Antigen Region | 457-483 aa |
| Gene ID | 8908 |
|---|---|
| Other Names | Glycogenin-2, GN-2, GN2, GYG2 |
| Target/Specificity | This GYG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-483 amino acids from the C-terminal region of human GYG2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GYG2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GYG2 |
|---|---|
| Function | Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It self- glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. |
| Tissue Location | Detected in liver (at protein level) (PubMed:9857012). Expressed preferentially in liver, heart, and pancreas (PubMed:9346895). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
References
Gibbons, B.J., et al. J. Mol. Biol. 319(2):463-477(2002)
Harris, R.A., et al. Proteomics 2(2):212-223(2002)
Zhai, L., et al. Gene 242 (1-2), 229-235 (2000) :
Mu, J., et al. J. Biol. Chem. 273(52):34850-34856(1998)
Orho, M., et al. J. Clin. Invest. 102(3):507-515(1998)
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