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KPNA1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant KPNA1.

  • WB - KPNA1 Antibody (monoclonal) (M01) AT2647a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (84.92 KDa) .
  • WB - KPNA1 Antibody (monoclonal) (M01) AT2647a
    KPNA1 monoclonal antibody (M01), clone 2A4-1B5 Western Blot analysis of KPNA1 expression in HeLa ( (Cat # AT2647a )
  • WB - KPNA1 Antibody (monoclonal) (M01) AT2647a
    Western Blot analysis of KPNA1 expression in transfected 293T cell line by KPNA1 monoclonal antibody (M01), clone 2A4-1B5.

    Lane 1: KPNA1 transfected lysate(60.2 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - KPNA1 Antibody (monoclonal) (M01) AT2647a
    Immunoperoxidase of monoclonal antibody to KPNA1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1 ug/ml]
  • E - KPNA1 Antibody (monoclonal) (M01) AT2647a
    Detection limit for recombinant GST tagged KPNA1 is approximately 1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P52294
Other Accession BC002374
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 2A4-1B5
Calculated MW 60222 Da
Additional Information
Gene ID 3836
Other Names Importin subunit alpha-5, Karyopherin subunit alpha-1, Nucleoprotein interactor 1, NPI-1, RAG cohort protein 2, SRP1-beta, Importin subunit alpha-5, N-terminally processed, KPNA1, RCH2
Target/Specificity KPNA1 (AAH02374.1, 1 a.a. ~ 538 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsKPNA1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.


1.Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery.Moriyama T, Nagai M, Oka M, Ikawa M, Okabe M, Yoneda Y.FEBS J. 2011 Mar 3. doi: 10.1111/ j.1742-4658. 2011.08079.x. [Epub ahead of print]2.Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.Nishimura AL, Zupunski V, Troakes C, Kathe C, Fratta P, Howell M, Gallo JM, Hortobagyi T, Shaw CE, Rogelj B.Brain. 2010 Jun;133(Pt 6):1763-71. Epub 2010 May 14.

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$ 350.00
Cat# AT2647a
Availability: 7-10 days
Bulk Size

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