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RHPN2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8IUC4 |
|---|---|
| Clone Names | 110901107 |
| Gene ID | 85415 |
|---|---|
| Other Names | Rhophilin-2, 76 kDa RhoB effector protein, GTP-Rho-binding protein 2, p76RBE, RHPN2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RHPN2 |
|---|---|
| Function | Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. |
| Cellular Location | Cytoplasm, perinuclear region |
| Tissue Location | Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the rhophilin family ofRas-homologous (Rho)-GTPase binding proteins. The encoded proteinbinds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may beinvolved in the organization of the actin cytoskeleton. [providedby RefSeq].
References
Abuli, A., et al. Gastroenterology 139(3):788-796(2010)von Holst, S., et al. Br. J. Cancer 103(4):575-580(2010)Kupfer, S.S., et al. Gastroenterology (2010) In press :Xiong, F., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1855-1861(2010)Hawken, S.J., et al. Hum. Genet. 128(1):89-101(2010)
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