KD-Validated Anti-Transcription Factor 7 Like 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC, ICC |
|---|---|
| Primary Accession | Q9HCS4 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB1985 |
| Calculated MW | Predicted, 63 kDa ; Observed , 63 kDa |
| Gene Name | TCF7L1 |
| Aliases | TCF7L1; Transcription Factor 7 Like 1; TCF3; Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box); HMG Box Transcription Factor 3; Transcription Factor 7-Like 1; TCF-3 |
| Immunogen | A synthesized peptide derived from human TCF3 |
| Gene ID | 83439 |
|---|---|
| Other Names | Transcription factor 7-like 1, HMG box transcription factor 3, TCF-3, TCF7L1, TCF3 |
| Name | TCF7L1 |
|---|---|
| Synonyms | TCF3 |
| Function | Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. |
| Cellular Location | Nucleus. |
| Tissue Location | Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium |

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