Anti-Contactin 1 Antibody
Rabbit polyclonal antibody to Contactin 1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
---|---|
Primary Accession | Q12860 |
Other Accession | P12960 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 113320 Da |
Gene ID | 1272 |
---|---|
Other Names | Contactin-1; Glycoprotein gp135; Neural cell surface protein F3 |
Target/Specificity | Recognizes endogenous levels of Contactin 1 protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | CNTN1 |
---|---|
Function | Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). |
Cellular Location | [Isoform 1]: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side |
Tissue Location | Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle. |

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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Contactin 1. The exact sequence is proprietary.

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