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Anti-Aquaporin 3 Antibody
Rabbit polyclonal antibody to Aquaporin 3
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q92482 |
| Other Accession | Q8R2N1 |
| Reactivity | Human, Mouse, Rat, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 31544 Da |
| Gene ID | 360 |
|---|---|
| Other Names | Aquaporin-3; AQP-3; Aquaglyceroporin-3 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Aquaporin 3. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | AQP3 {ECO:0000303|PubMed:7558005, ECO:0000312|HGNC:HGNC:636} |
|---|---|
| Function | Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:12239222, PubMed:30420639). Could also be permeable to urea (By similarity). Also participates in cell permeability to H2O2 and H2O2- mediated signaling (PubMed:20724658). In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair (By similarity). In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:O14520}. Basolateral cell membrane {ECO:0000250|UniProtKB:P47862}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O14520} |
| Tissue Location | Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Aquaporin 3. The exact sequence is proprietary.
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$ 195.00
$ 385.00
Cat# AP61506
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